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Images of the chick epiblast (Figure 1) indicate that cell boundaries often have significant deviations from a straight line, but a vertex model is a reasonable zeroth-order approximation of cell shapes.
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Models providing only a marginally higher degree of abstraction were found to have significant deviation in predicted frequency response.
There exist some cases however where this assumption failed: for example the frequency of the aboard ship the electrical network frequency may have significant deviation.
We selected the 5.5 h as the ending point because after this time the kinetic curves from pre-D analogs to D analogs have significant deviation from linearity, although after a long time (5~7 d), virtually all pre-D analogs are converted to their corresponding D analogs.
Three (COR101, NVHEQ040 and AHT023) of the selected loci also had significant deviations from neutrality in Connemara and one locus (AHT023) was monomorphic in Akhal-Teke.
Because FST may be influenced by unequal sample sizes, we limited our search for genes of interest to the nine high FST regions that also had significant deviations from expected heterozygosity in Thoroughbred.
However, individual markers had significant deviations of expected allele distribution.
Of the 5847 successful SNPs, 263 (4.5%) had significant deviations from Hardy-Weinberg equilibrium (HWE).
The other loci that had significant deviations from neutrality had negative DoS values (Cluster 1 (atpA) DoS = -0.54; Cluster 3 (fumC) DoS = -0.68).
In eight of ten sibships the genotype frequencies followed Mendelian expectations from crossing two individuals heterozygous at the S-locus (case 1), but two F1o sibships had significant deviations frequencies (one for one genotype, and one for two).
Fewer individual loci had significant deviations from the neutral expectation than were observed for Tajima's D as well, and only one locus in cluster 1 was significant for Fu & Li's D, but not Tajima's D (Additional file 1: Table S3).
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CEO of Professional Science Editing for Scientists @ prosciediting.com