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The VM mice used in this study have shown substantially shortened incubation periods compared with those from in earlier studies, which may have caused the alteration in ranking.
Studies on patients with longstanding RA have shown substantially higher prevalence rates of positive anti-CCP tests [ 2] than investigations based on patients with very early RA [ 1].
Basic in vitro studies in muscle strips from healthy myocardium have shown substantially increased contractility (measured as isometric twitch force) and prolonged contraction and relaxation times with mild hypothermia [ 11].
7 Many studies have shown substantially reduced social differences in drug use when health status have been taken into account, 6 8 9 which may indicate that filling of prescription medicine to a large extent reflects health status.
Two GIT isolates P. copri and P. stercorea also have shown substantially high percentage of predicted CDSs in the unique gene category, while in the sole skin isolate P. bergensis, 33% of the CDSs have been identified as unique genes.
For example, estimates from prospective US cohort studies using the AECC definition range from 64.2 13 to 78.9 12 cases/100,000 person-years, whereas estimates from Northern Europe (17 cases/140,000), 14 Spain (7.2 cases/150,000), 15 and Australia/New Zealand (34 cases/100,000) 16 have shown substantially lower rates.
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This prospective study of malignancy risk in 448 patients with NF1 has shown substantially increased relative risks for CNS and connective tissue tumours over the general population, contributing to an estimated overall risk of malignancy of 36%95%5% CI=27 46%) by age 70 years.
First tests have shown a substantially increased capacity and full cycle stability.
While these additives had no benefit during the assembly steps of either process (PCA and LCR), we have shown they substantially improve gene target-specific amplification and yield when added to the PCR step alone.
As such, the implants with a diameter of ca. 10 μm have shown to substantially reduce glial encapsulation.
Parsa et al. [ 35 ] have shown that substantially smaller ssDNA patches located within active genes may be substrates for the mutagenic activity of activation-induced cytidine deaminase (AID).
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