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Histone 4 is the only nucleosomal subunit present as a single copy gene and thus its down-regulation could have severe implication on the nucleosomal assembly during the P. falciparum schizont stage.
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"If replicated in less specific systems, this could have severe implications for crop productivity".
Even a restructuring would likely have severe implications on his 125-member staff.
"A change in the law would also have severe implications for the way society views disabled people".
"Coral reefs are sensitive to even small changes in ocean temperature and a 1C rise would have severe implications for the Great Barrier Reef and Ningaloo reef.
The NHS reforms will have "severe implications" for collecting and monitoring data about the health needs of the population across the country, warn experts.
Such a shift, if it takes place, would have severe implications for hopes of a consensual peace between Israelis and Palestinians, and for wider regional stability.
A sovereign debt restructuring "may have severe implications, both for the debtor's and the creditor's economies," Mr. Bini Smaghi said, according to a text of the speech.
Qin Dake, the other co-chair of the report, said combating climate change would have severe implications for people's lifestyles, especially in his home country of China, the world's most populous nation and its largest carbon emitter.
Ignorance of the fact that herbal products have effects analogous to conventional drugs can have severe implications and may also result in morbidity and mortality amongst patients.
The strength of a slope materials and groundwater depth (GWD) could have severe implications on the stability of the slope (Tables 11, 12, 13).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com