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The phrase "have run their course" is grammatically correct and can be used in written English.
It is often used to indicate that something has reached its natural or expected conclusion or has reached the end of its usefulness. Example: The trends of the past decade have run their course, and now it is time for a new wave of innovation and change in the industry.
Exact(59)
"Shine products have run their course".
And some of those ideas may have run their course.
Easy to Assemble and Escape My Life have run their course and not been recommissioned.
He also has a history of leaving high-profile positions before campaigns have run their course.
Pink Floyd have "run their course", according to the band's longtime member Dave Gilmour.
"We are disappointed these discussions have run their course without an agreement," Mr. Varma said.
USAID is to end operations in September when programs it is funding have run their course.
Some people deliberately destroy relationships before they have run their course, because they think they are going to end anyway.
CLASSICAL MUSIC LATE ROMANTIC Aug. 29-31 The big-shot summer festivals have run their course by Labor Day.
But improved anti-spam technology coupled with increased awareness means that they may have run their course.
He put Aug. 2 as the rough date on which those expedients would have run their course.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com