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Genetic analyses of mouse mammary tumor virus integration sites as well as functional studies using transgenic mouse models have provided considerable evidence supporting the cooperativity between the FGFR and Wnt pathways in mammary tumorigenesis [ 17– 20].
As noted in the Introduction, multiple studies have provided considerable evidence for a two-way clinical association between VTE and cancer, in that cancer elicits expression of procoagulant activities, contributing to the prothrombotic state in these patients, and the procoagulant activities themselves seem to elicit cancer growth, proliferation, and metastasis.
Furthermore, in the past decade a large number of studies have provided considerable evidence that assessment of tumor glucose utilization by FDG-PET provides an early readout for the effectiveness of therapy, that it correlates with the degree of histologic tumor regression and allows prediction of patient survival.
Human epidemiological studies and appropriately designed dietary interventions in animal models have provided considerable evidence to suggest that maternal nutritional imbalance and metabolic disturbances, during critical time windows of development, may have a persistent effect on the health of offspring and may even be transmitted to the next generation [ 22, 144- 149].
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Our laboratory has provided considerable evidence for BST using a variety of research approaches.
Recent research has provided considerable evidence that visits to near-natural everyday landscapes promote psychological and physical health.
Over the past several years, our group has provided considerable evidence that the expression of sigma-2 (σ2) receptors may serve as a biomarker of tumour cell proliferation.
Researchers have provided considerable yet mixed evidence in this regard [6].
The genome organization and gene content of E. cuniculi represents the first evidence of microsporidia genomic reduction (2.9 Mb) and has provided considerable functional insight on the evolution of microsporidia-host relationships at the biochemical and molecular levels.
Furthermore, the buses optimize efficient energy use and the implementation process has provided considerable employment opportunities.
First recognised by Bouillard in 1823 and later described by Trousseau in 1844, multiple studies have since provided considerable evidence for a clinical association between VTE and cancer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com