We have previously generated an ezh2+/ul2 mutant line using the TALEN technology26.
We have previously generated epidermal growth factor expressing Lactococcus lactis (EGF-LL) using bioengineering approach, and shown that feeding newly-weaned piglets EGF-LL improves digestive function.
We have previously generated epidermal factor expressing Lactococcus lactis (EGF-LL) using a bioengineering approach, and shown that EGF-LL fermentation supernatant enhanced newly weaned pigs growth.
As antibody fragment engineering has emerged as an economic alternative to mAb drugs via bacterial production, we have previously generated FM318, a recombinant Fab adopted from cetuximab.
By expressing human occludin and CD81 in an outbred ICR strain (C/OTg), we have previously generated an immune-competent humanized mouse permissive for HCV persistent infection19, and have successfully applied to a number of studies19,20,21,22,23.
We have previously generated human IgG1 antibodies that were engineered for reduced binding to the classical Fcγ receptors (FcγRI III) and C1q, thereby eliminating their destructive effector functions (constant region G1Δnab).
We have previously generated transgenic mice that overexpress GSK3beta in forebrain regions including dentate gyrus (DG), a region involved in learning and memory acquisition.
We have previously generated long-term stable, monosized, highly crystalline Fe3O4-ZnO, Au-ZnO, Ag-ZnO, and hybrid-phase iron oxide nanoparticles [27-30] [27-30]
We have previously generated R5 clade C SHIV (SHIV-C) strains [1], [10], [11].
We have previously generated an immortalized cell line of human microglia, HMO6, which carries morphologic and phenotypic expression characteristic of primary human microglia [18], [19].
We have previously generated pre-oxidized recombinant MHC class I molecules of a quality that allows virtually complete folding and peptide-MHC complex formation[11].
