Sentence examples for have previously circulated from inspiring English sources

Even though a single dose of A/H1N1/2009 vaccine appeared to be sufficient to fulfil regulatory criteria for 2009 pandemic influenza vaccine [ 9, 10, 12- 16], this may not be the case for future pandemic influenza strains depending on how antigenically and genetically distinct they are from strains which have previously circulated in humans.

The first collection of Donne's poems was published in 1633, two years after his death — they had previously circulated only as copied manuscripts among a coterie.

Age specific seroprevalences against pandemic H1N1 (A/California/7/2009) were measured and compared to seroprevalences against H1N1 strains that had previously circulated in the population in 2007, 1957, and 1918.

Phylogenetic analysis of 2008 and 2009 isolates support their inclusion into DENV-4 genotype II, forming a lineage distinct from strains that had previously circulated in the region.

As shown in the Table, the concern that swine influenza would appear in 1976 was supported by seroarcheology, evidence in serum samples collected before, for example, 1968 that an A (H2) and A (H3) virus had previously circulated (6 ).

In addition, subtypes of influenza A viruses that have not previously circulated among humans occasionally cross from animal reservoirs, raising the spectre of a pandemic.

These introduction events are referred to as antigenic shift, when a virus with HA and NA molecules that have not previously circulated widely in humans is introduced (probably through recombination with an avian or animal virus) and spreads effectively.

We have previously reported that circulating biomarkers of bone resorption were substantially elevated during critical illness whereas markers of bone formation were low [1].

We have previously detected peak circulating levels of MIF, 6 hours post CPB.

We have previously reported that circulating sclerostin is increased in T2DM and its relationship with bone turnover and bone mass.

We have previously demonstrated reduced circulating levels of IL-7 in active rheumatoid arthritis (RA) compared with health [ 1].