Comparisons of the human and the chimpanzee genomes have revealed poor conservation of recombination landscapes, in contrast to the high level of DNA sequence conservation observed among these species [5], [6].
We included the comparative analyses of other interaction domains as previous analyses have revealed poor conservation of protein-protein interactomes between Drosophila and human.
Even though others have demonstrated poor conservation of binding sites across species for some TFs [ 30, 32], we noted that higher peaks generally resided in regions of higher sequence conservation for many TFs (6 and 4 TFs significant in K562 and HeLa-S3, respectively).
However, homologous ncRNAs typically have poor sequence conservation which considerably limits the applicability of conserved region detection towards discovery of species specific ncRNAs [5], [21].
Integrated Ubl domains are stretches of 45 80 amino acids that share the β-grasp fold of Ub, but often have poor sequence conservation among subfamilies (Kiel & Serrano, 2006; Burroughs et al, 2007).
Upon further examination, these proved to have poor sequence conservation in the amino terminal region.
The results show that the different types of numerical oscillation in pressure field are generated when fully conservative form or interpolation of conservative variables is selected, while quasi-conservative form generally has poor mass conservation property.
Patients who suffer superficial recurrences of breast cancer, be it in their chest wall following mastectomy, or in their breast after breast conservation, typically have poor clinical outcomes.
Such identification has not always been possible due to the poor conservation of worms present in histological sections.
Although much needed, bringing in funds in this way would reinstall the monopoly of conservation by governments, several of which have poor track records.
