None of the patients had optimal control of all CRFs.
After 12 months, 102 of the 103 (99%) patients who completed the study had testosterone levels below castrate threshold, and 91 patients (88%) had optimal control of testosterone.
Among participants with obesity, only one in four with hypertension achieved recommended blood pressure levels, less than one-third with elevated LDL cholesterol had optimal control of these values, and only one in six participants with diabetes achieved fasting blood glucose <126 mg/dl.
Based on a recent analysis of trends in diabetes in the United States, while use of oral medications increased and glycemic control improved overall, a substantial portion of the United States population does not have optimal glycemic control [ 4].
In Australia, patients in general practice were more likely to have optimal HbA1c control than those visiting specialist clinics (57% versus 38%).
In addition, the ADA suggests that all levels of physical activity can be performed by people with type 1 diabetes who do not have complications and who have optimal blood glucose control [ 33, 37].
Females with diabetes are less likely than males to have optimal blood glucose control (A1C <7%), to be prescribed aspirin and lipid-lowering medications, and to achieve recommended blood pressure and LDL cholesterol levels (29, 30).
In addition, MPI ischemia and infarction were more frequently demonstrated in those who had poor glycemic control compared with those who had optimal glycemic control and when compared with those without diabetes.
In regards to glycemic control at the time of randomization, stratified analysis showed similar effects of the intervention in those who had optimal glycemic control (baseline A1C <7%, n = 46) as compared with those who did not (baseline A1C ≥7%, n = 314; results not shown).
Only 7% of women had optimal glycemic control (A1C <6.1%) at their first antenatal visit, increasing to 23 and 25% at 26 and 34 weeks' gestation, respectively.
