In other situations, we know that recurrent mutations or migrations have occurred continuously in the population and consequently perturbed the LD structure.
Considering that the proestrus-estrus phase is associated with higher circulating concentrations of steroid hormones recognized by the GABAA receptor [ 43] and that diazepam effectively targets GABAA receptors, overstimulation of this receptor may have occurred, and female rats may have consequently exhibited hypoactivity in the open field test.
We believe that Hp-mediated induction of PPARγ might be a feedback mechanism to partly suppress the exaggerated inflammation that may have occurred through NFκB and AP-1 and consequently perturbed the long-term survival of Hp in the host.
Other self-reported MetS indicators might have been underestimated, but such information bias is likely to have occurred similarly in cases and controls, and, consequently, should have led to an attenuation of the real association [ 16, 34].
In addition, SHMT is structurally conserved because of its critical metabolic role; consequently, very few structural changes have occurred during evolution.
Such problems do not necessarily result in occupant complaints and, consequently, are not even recognized to have occurred.
Given the way in which decentralization occurred it was not possible to use an experimental design with experimental and control groups; consequently clear attribution of any changes that may have occurred to decentralization is not possible.
Furthermore, responder bias may have occurred as interviews took place in a school environment and students may have, consequently, over-emphasised the importance of knowledge obtained in schools.
In regular healthy subjects, the highest MVC would have occurred at torque levels where VA would have been calculated to be ∼90%, and consequently the EMG torque relationship would most likely have been considerably less curvilinear.
For example, the appearance of polymorphism through ancient hybridization (many early hybridizations must have occurred in the early Triticeae) followed by incomplete sorting of ancestral polymorphism could lead to intra-specific variation in a diploid and, consequently, in a polyploid.
