Sentence examples for have now validated from inspiring English sources

Preclinical data have identified N-type VGCCs (Cav2.2) as key participants in contributing to these Ca2+ signaling events and clinical data with the peptide blocker Prialt™ have now validated Cav2.2 as a bona fide target for future drug discovery efforts to identify new and novel therapeutics for neuropathic pain.

We have now validated several panels of genes that characterise this BRCA1-deficient breast cancer profile.

Per reviewer's request, we have now validated this result using two additional independent Rpl5-targeting siRNAs in yet two independent isolates of primary Rps27l +/+ MEFs from different breeders.

At least seven separate published studies have now validated the presence of this signature in the peripheral blood of lupus patients [ 18- 24].

A large number of preclinical studies have now validated mutated BRAF as a bona fide therapeutic target in melanoma (Hingorani et al, 2003; Karasarides et al, 2004; Sharma et al, 2005).

However, to address this Reviewer comment, we have now validated that we are seeing the same downstream effects with sorafenib observed previously with erastin, including glutathione depletion (Yang et al (2014) Cell) and lipid peroxidation (Dixon et al. (2012) Cell).

OnStar has now validated 90 million vehicles manufactured in the last 10 years as compatible with OnStar FMV – up from 55 million when the product was announced at the International Consumer Electronics Show in January.

For decades, we've had factions of Congress engage, at every turn, in tactics that limit access to equality -- and the Republican Party has now validated some of the most outlandishly bigoted and repressive beliefs about the LGBT community.

A growing number of mines in the Democratic Republic of Congo have now been validated as conflict-free, making it easier for companies to keep conflict minerals out of their supply chains.

Changes in UO have now been validated in several studies as early and sensitive criteria for AKI [12, 13].

While elastographic methods of TE and ARFI have now been validated for the assessment of fibrosis, other elastographic technologies are emerging and are likely to become more widely applied.