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"Sometimes you see that it's a fantastic day and if you have no important deadlines you can just call in and say: 'I'm taking a duvet day today,'" says managing director and founder Felicitas Betzl.
SB is most efficient and effective if the following assumptions are satisfied: (i) second-order polynomials are adequate approximations of the input/output functions implied by the simulation model; (ii) the signs of all first-order effects are known; and (iii) if two inputs have no important first-order effects, then they have no important second-order effects either (heredity property).
Percentage of acetonitrile in mobile phase, flow rate and pH; an increase in the flow rate results in a decrease of the drug found concentration, while the percentage of organic modifier and pH have no important effect on the response.
For robustness test three factors were considered: percentage v/v of acetonitrile, flow rate and temperature; an increase in the flow rate results in a decrease of the drug found concentration, while the percentage of organic modifier and temperature have no important effect on the response.
The paradox is that DDT is widely considered to be the most effective chemical for malaria control and, unfortunately, is widely considered to have no important function other than killing mosquitoes.
In conclusion, infliximab appears to have no important beneficial effect upon pain associated with deep endometriosis.
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Greece imports most of its needs and has no important allies in its confrontation with the EU.
"In 1936, money had no important role," Samuelson recalled.
He had no important backers, no ties to the Democratic Party and no political skills.
He has no important weakness, even if there is nothing very special either.
Although Mr Quine has no important theorem to his name he wrote on mathematical logic with ingenuity and wit.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com