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I am perfectly convinced by that you have no defect.
We chose BATF3−/− mice because they lack functional cDC1s18 but have no defect in granulocyte number (Supplementary Fig. 4d).
This strongly suggests that age3Δ cells have no defect in ergosterol biosynthesis, a process that is targeted by azoles.
Loss-of-function genetic studies revealed that unlike the Drosophila neur mutants, Neur1−/− mice have no defect in neurogenesis and embryonic development, possibly due to a functional overlap with Neur2 [17], [17].
Mutants lacking both scaffolds have no defect in total surface receptors (assessed by muscimol-activated currents).
The importance of this mechanism requires clarification, however, because p62/SQSTM1 null cells have no defect in Parkin-mediated mitophagy (17, 18).
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The name is stupid because if the trust is done correctly it will have no defects, intentional or otherwise.
Since strains A-2A and A-4 were almost completely rescued by ferrous iron, they appeared to have no defects in their systems for direct iron uptake.
The abundant proteoglycan, aggrecan, is resorbed from growth plate cartilage during endochondral bone ossification, yet mice with genetically-ablated aggrecan-degrading activity have no defects in bone formation.
However, synapsis mutants generally have no defects in SPO-11-mediated DSB induction, and the majority of DSBs are ultimately repaired.
For example, progeria patients have no defects in their mental and intellectual abilities, which suggests that the brain may be protected from, and/or insensitive to, and/or unaffected by, the expression of the progeria mutation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com