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Hospital complication indicators have been computed based on administrative data for more than 15 years and risk-adjustments have matured substantially over this period [ 22].
The phase 2 OS data, which may have matured substantially by that point, does not contribute to the phase 3 adaptation.
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"Steve has matured substantially in his C.E.O.
Since its initial funding in May 2006, our CCNE program has matured substantially into a strong multidisciplinary program with expertise and infrastructure to support the growing field of cancer nanomedicine.
The report concluded that while the Triple P programme "may have been ineffective", there were reasons for optimism as "the parenting support infrastructure in Glasgow has matured substantially".
But I have matured.
The Lakers have matured.
"We have matured," Wenger said.
I think they have matured.
I think I have matured.
"I have matured as a fighter.
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