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Almost all developing countries have major problem for overpopulation and its generated wastes (Kaviraj and Sharma 2003).
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Many other sporting nations have major problems.
"The theories we had for how the sunspot cycle works have major problems".
"We do have major problems with the contracts," Dennis Tompkins, the comptroller's spokesman, said.
"I don't think there is any reason to think we will have major problems".
Twitter grew so quickly that it started to have major problems dealing with all the customers.
Already NHS services have major problems recruiting and retaining staff to work in the area.
In the United States, we have major problems with both our delivery and insurance systems.
Most children don't have major problems and don't need this blunderbuss of an intervention.
Otherwise, you are going to have major problems, like accidents that we have had," he says.
If the embryos do survive, they have major problems with brain and facial development.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com