Hence, the optical mapping has mainly applied for small genome organisms, ex.: bacteria (Zhou et al. 2004; Haas et al. 2009).
Participatory Design (PD) methods in the field of health informatics have mainly been applied to the development of small-scale systems with homogeneous user groups in local settings.
MR angiography and MR perfusion have mainly been applied for the study of acute pulmonary embolism, a key clinical entity to demonstrate diagnostic accuracy.
To date, these methods have mainly been applied to evaluate pharmaceutical interventions.
They have mainly been applied to study global topological properties of networks containing up to several thousand proteins [ 5, 6].
Estimators of gene connectivity have mainly been applied to summarize and compare the global structure of co-expression networks.
All three strategies, cognitive rehabilitation, training of dual-tasking abilities, and computerized interventions, have mainly been applied to individuals with stroke, with traumatic brain injury or elderly.
Bismuth-film electrodes have mainly been applied to anodic stripping voltammetry (ASV) and adsorptive stripping voltammetry (AdSV) techniques for metal ion analysis, although cathodic detection of nitrophenols [ 17, 27, 41] and amperometric detection of glucose [ 12] have also been reported.
Even though tools to construct gene modules have been developed, they have been mainly applied in datasets from relatively simple model organisms [ 4, 5, 9, 11, 13, 14].
2 In Spain, several tax reforms have accompanied the implementation of more restrictive tobacco regulations, but they have been mainly applied to manufactured cigarettes.
