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Companies have made large discoveries this year.
Some professors have made large amounts of money.
In particular, European and Japanese markets have made large gains.
They have made large soft-money contributions to political parties.
The Freys have made large investments to further improve and streamline the operations at Maison Jaboulet.
In more recent years, the Kochs have made large donations to the United Negro College Fund.
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As the economy has weakened, many businesses have made large-scale job cuts.
Advances in chromatin immunoprecipitation sequencing (ChIP-seq) have made large-scale repositories of epigenetic data available, allowing investigation of coordinated mechanisms of epigenetic markers and transcriptional regulation and their influence on biological function.
The depth and seriousness of the crisis have made large-scale State intervention indispensable, as currently observed in the United States, in the United Kingdom and in several other developed countries.
Historically, it is religion that has created the moral commitment -- and the loyalties that transcend tribal, regional, ethnic and linguistic affiliations -- that have made large-scale social progress possible.
The tremendous advances in DNA sequencing technologies that have taken place over the last few years have made large-scale sequencing and genome comparison studies accessible for many applications.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com