Brian Lanker, a photojournalist who showed that small-city newspapers could have large-scale impact through the empathetic and intimate visual portrayal of American lives, died Sunday at his home in Eugene, Ore.
While traditional donor-supported activities are critical to having large-scale impact, alone they probably won't get us where we need to be.
My company, Wonderloop, was announced recently as "The Social App of South by Southwest (SXSW) +Social Good" which is an incredible honor, however, I know a lot of people will ask how can a mobile application have large scale social impact?
Anthropogenic pollution of river waters caused by factors, such as industry, agriculture and human sewage, is an issue of great concern, since together with population growth and climate change, and it can have large scale adverse impacts on the surface water quality.
However, with the notable exception of all-trans retinoic acid (ATRA) in a subset of AML known as acute promyelocytic leukaemia (APL [10], and imatinib mesylate (Glivec) and its derivatives in chronic myeloid leukaemia (CML [11], few of these therapies have as yet had a large scale impact.
Studies which incorporate newer information technology may lead to more sustained changes as they are simple to administer, and can have a large scale impact by inexpensively involving a variety of health professionals and/or consumers [ 55, 56].
However, mesquite invasions are having large-scale negative impacts on native tree population stability, abundance, density and mortality in South Africa (Schachtschneider and February 2013; Shackleton et al. 2015b, 2015c) and natives are still being harvested in preference to mesquite.
The issue of land use (both direct and indirect) change in the bioenergy arena has large-scale policy impacts (e.g., RTFO [33], RED [31], EISA [32], LCFS [35], RSF2 [34]), through carbon payback and GHG accounting for market-mediated land use changes potentially associated with biomass use.
DSB detection by γ-H2AX foci has been used in studies of the effects of personal exposure to environmental agents such as air pollution, food toxins and industrial chemicals, all of which have the potential of large scale impacts on human populations as well as populations of other organisms.
While many organizations, globally and locally, are working to make resources available and to provide services and support to children affected by HIV and AIDS they have, to date, had little large-scale impact (Richter, Foster & Sherr, 2006; Richter, Manegold & Pather, 2004).
