Sentence examples for have investigated the safety of from inspiring English sources
Several phase I studies have investigated the safety of gefitinib at daily doses of 250 mg or 500 mg in combination with chemotherapy agents for first-line treatment of a variety of common solid tumors.
Some studies have investigated the safety of TCZ in RA patients [ 4, 13, 15, 32- 35].
A number of dedicated studies have investigated the safety of intravenous valproate in patients with epilepsy during the clinical development of this formulation.
Several clinical trials have investigated the safety and efficacy of some HDACis used as single agents in the treatment of multiple myeloma (MM).
Two phase I clinical trials that have investigated the safety and efficacy of the erlotinib-pemetrexed combination have been reported.
Two phase 1 trials combining bevacizumab and sunitinib have have investigated the safety and maximum tolerated dose of this combination.
A number of studies have investigated the safety afforded to children by the default value for the intraspecies factor either by considering ratios between young and adult animals or those of toxicokinetic and to a lesser extent toxicodynamic parameters between human adults and children.
Previous studies in the area of patient safety have investigated the safety climate in primary care in Albania.
Since the original safety warnings, several studies have investigated the neuropsychiatric safety of varenicline.
While SGAs readily cross the placenta, 14 the existing studies that have investigated the reproductive safety of these agents did not reach conclusive results due to the methodological limitations, small sample sizes and failure to assess SGAs in monotherapy.
The results of this study are consistent with those of several published studies that have investigated the efficacy and safety of free combinations of LABAs and LAMAs in patients with COPD [ 6, 18– 20], but this is the first to demonstrate the additive benefit of the two classes of long-acting bronchodilator in a combination device.
