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Patients with end-stage renal disease have increased circulating concentrations of oxidatively modified circulating proteins.
Numerous reports demonstrate that GDM women have increased circulating tumour necrosis factor-α (TNF), a pro-apoptotic peptide.
Conclusion: At birth, term appropriate-for-gestational-age infants born to mothers with asthma have increased circulating absolute nucleated red blood cell and lymphocyte counts compared with control infants.
The induction of circulating plasmablasts is increased in pregnant women versus controls (median fold-change 2.60 vs 1.49 [interquartile range, 0.94-7.53 0.94-7.53.67]; P =.03).Pregnant women do not havs impaired humoral immune responses to IIV and may have increased circulating plasmablast production compared to control women.
Many PV patients also have increased circulating granulocytes and platelets.
Further, hypertensive patients exhibiting chronic inhibition of the sympathetic drive have increased circulating adiponectin [36].
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The cows in the 5-d Cosynch protocol had increased circulating P4 at the time of PGF2α injection (2.66 ± 0.13 vs. 1.66 ± 0.13 ng/mL).
Lck-GM-CSF transgenic mice developed a disseminated histiocytosis and had increased circulating IL-17 producing T helper cells related cytokines.
Mice fed a high-fiber diet had increased circulating levels of SCFAs and were protected against allergic inflammation in the lung, whereas a low-fiber diet decreased levels of SCFAs and increased allergic airway disease.
As expected, control mice had increased circulating VEGF-R2-positive endothelial cells compared to resveratrol treated mice (Fig. 6C).
In the present study, we found MyD88-deficient mice fed a HFD had increased circulating levels of insulin, leptin and cholesterol, as well as liver dysfunction (increased induction of ALT levels, increased activation of JNK and cleavage of PARP), which were linked to the onset of severe diabetes.
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