Sentence examples for have implications for the expression from inspiring English sources
If DNA methylation and chromatin states are broadly maintained following the duplication of a region then this is likely to have implications for the expression of genes in close proximity to the new duplicon.
This arrangement appears to have implications for the differential expression of the cluster, where cis-regulatory elements associated with estrogen induction [ 43, 44] and recruitment of the transcription initiation complexes are concerned.
These results have implications for the interpretation of expression experiments, especially in cases for which chromatin immunoprecipitation data are unavailable, incomplete, or ambiguous.
The physiological expression of TERT within normal epithelial cells that retain proliferative potential and its presence at the earliest stages of tumorigenesis have implications for the regulation of telomerase expression and for the identification of cells that may be targets for malignant transformation.
These observations have implications for the optimization of CAR expression and function.
Our findings have implications for the experimental design of comparative expression studies that use single-species microarrays, and for our understanding of divergent expression in hybrid clawed frogs.
Characterizing the mechanisms involved in this differential regulation of CD36 expression may have implications for the prevention of high cardiovascular mortality observed in chronic inflammatory diseases.
The human TPH2 promoter polymorphism rs11178997 impacts on TPH2 expression, which might have implications for the development and function of the serotonergic system in the brain [ 13].
Our findings thus provide insight into the regulatory mechanisms underlying mPGES-1 expression and may have implications for the design of new anti-OA and anti-inflammatory drugs.
These findings might have implications for the design of transgenes in relation to optimizing their expression.
The high degree of variation in this study and the fact that RPS19 seems to play a central role in a large proportion of DBA patients suggest that regulatory networks altered by one or the other SNP may have implications for RPS19 expression.
