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Furthermore, VEGF-positive patients generally have higher responsiveness to anti-VEGF drugs than VEGF-negative patients [16].
Lean fish may have higher responsiveness to low dietary n-3 LC-PUFA, up-regulating the biosynthetic pathway when fed dietary VO.
Calprotectin was found to have higher responsiveness to change than CRP, SAA and ESR (Table 3), with large SRM at 1 month, moderate at 3 and 6 months and small at 12 months examination.
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To be useful for outcome assessment in clinical practice or research, an instrument should have high responsiveness, which is strongly related to the level of agreement [ 24] Limits of agreement should be smaller than the minimum clinically relevant difference one wants to detect.
In addition, the EQ-5D had higher responsiveness; improvements utilities for patients with different severity levels were higher with the EQ-5D.
The authors demonstrated that ASDAS had higher responsiveness compared to BASDAI and CRP and thresholds for BASDAI at 20 mm or 50% improvement corresponding to an ASDAS of 1.38 and 1.95, respectively.
We compared various measures of patient-reported outcomes in revision hip arthroplasty and showed that the WOMAC and SF-36 pain and physical function scales and the EQ-5D index had high responsiveness, and that a simple visual analog scale for was equally responsive or even more responsive.
All instruments had high responsiveness as measured by the SRM (1.05 1.63).
For the 3-month follow-up group, all instruments had high responsiveness ranging from 0.84 1.48.
Subsequent studies have suggested that the SPADI is highly correlated with the DASH and ASES in patients with shoulder arthroplasty [ 14] and has high responsiveness to detect change following an initial episode of shoulder pain [ 7] or a spectrum of shoulder conditions [ 17].
EQ-5D seemed to have higher construct validity and responsiveness in these patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com