Shedding of neoplastic colonocytes is known to be higher than the shedding of normal healthy colonic cells in stool; therefore, CRC-specific biomarkers should have high specificity.
These ligands have high specificity to receptors and other cancer-specific targets that are overexpressed on the surface of tumor cells, such as glycans [12].
Good confirmatory tests have high specificity, because you want your test to be specific and not mislabel those without the characteristic as having it.
Although monoclonal antibodies have high specificity, their usefulness in the clinic, especially against solid tumors, has been limited.
While antibodies can have high specificity, the doses required to treat patients, particularly for a chronic condition, are typically large.
The competitive experiments of the nine phthalates with some of their analogues on the sorbents illustrated that the DMIPs sorbents have high specificity for the phthalates.
The selective recognition capacity of the three GAs with four analogues on the sorbents illustrated that the DMIPs sorbents have high specificity for GAs.
We prioritized several potential pan-cancer therapeutic targets that are likely to have high specificity for activated CAFs and minimal toxicity in normal tissues.
However, inhibitors for shikimate pathway enzymes should have high specificity for X. fastidiosa enzymes, since they are also present in plants.
The development of immunoadsorbents that have high specificity for immunoglobulin and no immunogenicity is essential for immunoadsorption treatment of autoimmune diseases.
The B-B4 mAb has been shown to have high specificity for syndecan-1, but it is not cytotoxic for myeloma cells [14].
