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Analysis of TR paratopes and pMHC epitopes revealed that although there are no absolutely conserved residues found in interacting regions of both TR and pMHC ligands, there are vital conserved positions on both interfaces across TR/pMHC-I and TR/pMHC-II structures that could have fundamental implication for peptide vaccine design.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com