Sentence examples for have functional effect from inspiring English sources

To further identify SNPs that putatively have functional effect at the protein level, we analyzed the 47,163 central SNPs with four methods.

As to Dnmt2, one possibility is that Dnmt2 doesn't have functional effect to the embryo development, or our RNAi didn't work.

We assume that rare variants are more likely to have functional effect than common variants and among the rare variants the non-synonymous single nucleotide variants (nsSNVs) have the strongest impact.

These findings suggest that RIC may have functional effects on myocardial contractile function [ 1].

In silico analysis of the p.P49L mutation suggested that it could have functional effects.

Building on this, we tested whether common LPA species present in blood (16:0, 18 1, and 18 2) have functional effects on the carotid body output using an en bloc perfused carotid body preparation (Fig. 1c 33,38.

It is thus likely that this result is caused by linkage to a nearby rare SNP that does have functional effects.

Bovine milk contains cytokines like IL-10 that can have functional effects on immunological structures in the gut mucosa.

We emphasize the difference because exapted interactions typically have functional effects on plant fitness despite having evolved out of this functional context.

Several single nucleotide polymorphisms within genes which comprise the fibrinolytic system have been shown to have functional effects on the rate of blood clot degradation.

Hence, all genes at the IFIH1 locus may be interesting potential candidates in the etiology of T1D even though nsSNPs are more likely to have functional effects.