Sentence examples for have functional consequences from inspiring English sources

These findings suggest that for many of these loci the reference allele could have functional consequences or even being a loss/gain-of-function variant.

"Our work reveals that structural variations are often likely to have functional consequences.

These differences in glycosylation are likely to be the result of post-translational processing and may also have functional consequences.

These frequent DDR gene alterations in many human cancers have functional consequences that may determine cancer progression and guide therapy.

A major motivation for complete sequencing of genomes is to identify variants that are likely to have functional consequences based on their annotation.

For HIV-1, GWAS demonstrate that some naturally selected variants in the host-pathogen protein interaction networks continue to have functional consequences for susceptibility to these pathogens.

Stochastic slowdown of reaction flux caused by molecular noise in living cells may have functional consequences, which the present theory may be used to quantify.

Of special interest are features that may have functional consequences.

Future studies are necessary to determine which mutations have functional consequences and whether any associated therapeutic vulnerabilities can be exploited.

These decreases in AC activity can be reversed by disabling Galphai with pertussis toxin, indicating that the age-dependent increases in Galphai expression and activation have functional consequences.

For instance, study [52] (PubMed ID: 16378688) showed that SP1 deposition in hyper-phosphorylated tau deposits may have functional consequences in the pathology of AD.