Sentence examples for have evolved to integrate from inspiring English sources
The upstream regulators Dachsous and Fat and the downstream effector Yorkie, and its transcriptional partners, must have evolved to integrate multiple inputs and to activate different targets.
The newly described role of these kinases in regulating starvation-induced autophagy raises the possibility that this arm of the MAPKAPK family (sometimes referred to as the 'p38 module') may have evolved to integrate autophagy induction with diverse other cellular functions required for cellular adaption to stress.
In this review, we discuss the histologic, immunohistochemical, cytogenetic, and clinicopathologic aspects of these differential diagnoses and illustrate how the classification of RCC has evolved to integrate both the tumor's microscopic appearance and its molecular fingerprint.
Living cells have evolved to perceive and integrate different signals from their surroundings and to respond by modulating the appropriate gene expression.
Considering that some MAPKKKs are capable of activating multiple MAPK modules or activating the same modules for different durations, the diversity of the MAPKKKs may have evolved to allow cells to integrate specific MAPK pathways [ 1].
This macromolecule assembly exemplifies how plants (and other organisms) have evolved to respond efficiently to changes in the environment by integrating several pathways through key master regulators.
Beyond the techniques that have evolved to relate and exchange information across distinct databases, there is a need for the definition of common 'languages' to describe integrated information.
This again can be related to the effect of the pleiotropic gene, which has evolved to affect a nonrandom set of related functions that are integrated.
Hence, it is clear that computational methods for inferring domain-domain interactions have been constantly evolving to integrate and take advantage of the vast amount of updated annotation data emerging in many dimensions.
Plants have evolved mechanisms to integrate various environmental signals, including photoperiod and vernalization, to enable flowering under conditions that optimize seed production [ 1, 2].
