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Either decision would have entailed significant changes in the social practice of patenting with, arguably, significant costs.
Recent insights into specific features of MS induction and pathogenesis have entailed significant changes in the therapy of this autoimmune abnormality.
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Herbivorous mammals rely on resident gut microorganisms to gain energy from their main food sources, and this has entailed major changes in digestive anatomy and physiology that allow efficient microbial fermentation to take place alongside the recovery of dietary energy by the host.
Both sides have undergone significant changes in personnel since.
Two unconscious patients have come in with blood-stained notes pinned to their blankets, but most have entailed pure guesswork.
The club has just had some other significant changes.
The Seahawks uniform has undergone significant changes.
Under pressure from investors, Mr. Prince has made significant changes.
Library Information Technology Libraryy IT) has undergone significant changes over the past two years.
The chick morphology had no significant changes.
The placebo group had no significant changes.
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