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Attempts at exhaustive scans for imprinted genes in humans have encountered several drawbacks, including the challenge of using the most appropriate tissue and developmental stage, a problem exacerbated by reliance on lymphoblastoid cell lines (LCLs) [4].
Apart from methodological problems, application of the chronic stress approach has encountered some conceptual drawbacks.
Respondents were also asked to judge the effectiveness of the methods, tools and techniques they had used and to report any limitations or drawbacks they had encountered.
Both have potential drawbacks.
They have three drawbacks.
It does have some drawbacks.
The plans have some drawbacks.
Does it have any drawbacks?
Small hotels have their drawbacks.
But they have major drawbacks.
Drones do have some drawbacks.
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