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We have discovered a problem with the standard approach to analyzing DNA methylation at functional regions from genome-wide data and have shown that it affects comparative studies, resulting in false and exaggerated annotation of methylation differences in the human methylome.
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Last month, for example, Amazon erased "1984" and "Animal Farm" from its customers' Kindles by remote control, having discovered a problem with the rights.
The company said it had discovered a problem with the way the vehicles cross bike lanes, raising serious questions about cyclists' safety.
Several justices, including Anthony M. Kennedy, David H. Souter and John Paul Stevens, expressed concern about shielding manufacturers during a regulatory "hiatus," after a manufacturer had discovered a problem with an approved device but before the F.D.A. had learned of it or taken action.
The Financial Times quoted an Ethiopian manager in Britain as saying that maintenance workers had discovered a problem with the plane's air-conditioning system during a routine inspection and had seen sparks but no flames.
But after several weeks of delays, a consular official in Sana told him that the United States authorities had discovered a problem in his file: His father apparently had not satisfied the requirements for conveying citizenship to him two decades earlier.
But revolutionary fictionalism is implausible as well; given the track records of philosophers and mathematicians, it would be "comically immodest" for philosophers to presume that they had discovered a problem with mathematics (Burgess, 2004, p. 30).
But mobile phone users looking for improved phone reception and service have discovered a new problem: technical glitches and delays in making the number transfers.
Researchers from the Massachusetts Institute of Technology may have discovered a way around the problem.
The problem is that the resulting material is as sensitive as its most sensitive component.Adam Matzger of the University of Michigan and his colleagues have discovered a way around that problem by using a process called co-crystallisation, which is commonly used by drugmakers to modify the physical properties of a pharmaceutical.
In a city where graffiti abatement is swift — property owners are fined if graffiti is not immediately removed, and the city spends $20 million on the problem — taggers have discovered a way to ensure that their mark has staying power.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com