Exact(2)
SearchDOGS will find missing genes, but if the majority of genes in a species are missing SearchDOGS will have difficulty pinpointing the locations of new genes relative to those already identified.
Although linkage analyses have met with some success (Houlihan et al. 2009; Dick et al. 2006; Luciano et al. 2006; Posthuma et al. 2005), these studies lack power to detect common variation and have difficulty pinpointing the variant of interest (Balding 2006).
Similar(58)
Scientists had difficulty pinpointing the precise cause of the deaths, for neither melamine nor cyanuric acid are thought to be particularly toxic by themselves.
And they had difficulty pinpointing blame on Monsignor Lynn — a single, midlevel official — when there was evidence that other, more senior church officials, starting with the cardinal at the time, were involved in efforts to hush up the scandal.
Supposedly situated in the early 1990s, the show has difficulty pinpointing its time and place.
Despite the increase in winds the center of circulation remained very broad, with Reconnaissance Aircraft having difficulty pinpointing the center.
Non-coding DNA may also be the reason why linkage studies that consistently point to a chromosomal region (such as linkage to the short arm of chromosome 6 for reading disability) have had difficulty pinpointing the gene responsible for the linkage.
The most common probes, which use fluorescent markers or radioactive labels to pinpoint the virus's location in a tissue sample, sometimes have difficulty distinguishing the target HIV RNA and DNA from surrounding cellular components.
I have difficulty staying asleep.
They have difficulty integrating.
"I have difficulty breathing..
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