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SECSTR (Fodje and Al-Karadaghi, 2002) is another variant which improves the detection and assignment of π-helices which both DSSP and STRIDE have difficulty characterizing (Martin et al., 2005).
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Another limitation of our study is that we used a broad definition of SCALE-UP 'users' because almost all faculty members make modifications and have difficulties characterizing their use.
Due to the heterogeneous nature of these aggregates, experimental techniques such as X-ray crystallography and NMR have had difficulty characterizing their structures.
However, the laser diffraction and phase Doppler particle analyzers have difficulty in accurately characterizing sprays with a wide range of droplet sizes and very large droplets, especially if a large number of droplets are aspherical.
I have difficulty staying asleep.
They have difficulty integrating.
"I have difficulty breathing..
Have difficulty?
Some have difficulty conceiving.
They have difficulty planning.
Have difficulty staying awake.
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