Gene targeting studies have demonstrated that changing the endogenous distribution of RA can have severe consequences for the developing embryo.
2 3 The CHD mortality declines have demonstrated a changing relationship with socioeconomic status (SES).
Evidence from the fossil record [ 65, 66] and from reconstructions based on molecular data [ 59, 67, 68] have demonstrated that changing climate generates a profound influence on species' range expansion and contraction, as well as in their patterns of genetic diversity and structure [ 3, 6, 7, 10, 11, 68- 71].
In this case we have demonstrated that simply changing the size of the Ag can clearly impact on Tfh differentiation.
A number of implementation strategies have been described and evaluated in the literature that have demonstrated some effectiveness in changing clinician practices in a variety of settings.
Gender transformative interventions, which seek to reconfigure gender roles in the direction of more gender equitable relationships, [ 16] have demonstrated some success in changing norms and reducing risk behaviors [ 17– 17].
This study has demonstrated the changing prevalence of antibiotic resistance in MRSA in Kuwait and determined the genetic location of their resistance determinants.
This study has demonstrated that changing environments between an operating theatre and a tutorial room does not significantly affect the short-term recall ability of participants.
This is changing — drones have demonstrated key in-flight refueling technologies — but the US is just getting to the first engineering stages of putting air-to-air missiles on unmanned aerial vehicles.
Additionally, as recent outbreaks of severe acute respiratory syndrome (SARS) and avian and pandemic influenza have demonstrated, these new threats are changing the way that outbreaks are dealt with from mainly local and national responses to regional and even global approaches (2– 4).
