In support of this notion, there is evidence to suggest that impaired endocytosis and consequent prolonged signaling can have deleterious consequences [ 16].
Thus, while type I interferons exert some anti-inflammatory effects in the current study, systemic viral infection and consequent CNS activation of pro-apoptotic pathways could still have deleterious consequences for those with existing CNS pathology.
So we caution that the squeeze of this decade will have deleterious consequences in the next".
It is no genetic mystery that inbreeding, which is the inevitable consequence of purebred breeding, will have deleterious consequences.
"I hope that with a bit of time, and a bit of a further thought and discussion with the charities that I and others are interested in, the government can come up with a plan that does not have deleterious consequences".
Initial mistakes have deleterious consequences [41].
Similarly, excessive neutrophil activation could have deleterious consequences, notably by sustaining coagulation through NETs formation.
Both blunt denial of the problem and overreaction may have deleterious consequences.
Removal of TIVAP may have deleterious consequences in critically ill patients.
When considering such problems, spurious numerical cavitation can be quite common and have deleterious consequences on the flow field stability, accuracy, etc.
Sleep alterations are known to have deleterious consequences in healthy subjects, but the paucity of data in the literature [4 7] makes it difficult to determine the impact of sleep abnormalities in ICU patients.
