Exact(1)
By contrast, many studies have critically implicated the NAc in controlling intake of alcohol and other drugs of abuse (Belin et al. 2009; Koob 2013; Marty and Spigelman 2012).
Similar(59)
Anatomically, the DLFC has close connections to the parietal and premotor cortices, via the thalamus to the cerebellum (Hoshi, 2006) and also to regions that have been critically implicated in mentalizing, such as the temporo-parietal junction (Bzdok et al., 2012b; Kucyi et al., 2012), the anterior cingulate cortex (ACC), and right-inferior frontal gyrus (IFG) (Cieslik et al., 2013).
Both oxidative stress and TNFα have been critically implicated in the progression of NAFLD5.
The same caspase inhibitors also have been critically implicated in apoptosis of tobacco cells induced by isopentyladenosine and menadione [17], [18], [19].
In addition to its well known role in the mediation of emotions [29], [30], the amygdala [particularly its basolateral division (BLA)] has been critically implicated in the emotional potentiation of memory by facilitating information processing and storage in other structures, notably the hippocampus [31], [32], [33].
Therefore, critically implicated regions may have been overlooked.
The ACC has connections with various brain areas including the limbic system, which is critically implicated in affect [ 54].
Among various immune cells, CD4+ T cells are critically implicated in pathogenesis of RA [ 22].
52 Indeed mitochondrial dysfunction is critically implicated in the pathogenesis of PD.
Accumulating evidence suggests that NF κB is critically implicated in various inflammatory diseases.
Genetic approaches in mice have recently implicated hunger and arousal hormones/peptides in mediating FAA [6] [10], furthering the notion that hypothalamic circuitry is critically involved in mediating anticipatory activity (AA).
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