There are undoubtedly lots of factors that have contributed to these trends, but trade is certainly among them.
"Senator McConnell's own alma mater, the University of Louisville, has sponsored talks about 'how climate change is a measurable reality and how people have contributed to the trends,'" the letter says.
7 Poorer access to specialised clinical cardiovascular care and economic disadvantage have contributed to these trends.
Finally, we determined whether there have been changes in histopathologic factors that could have contributed to observed trends.
Among environmental exposures that may have contributed to the trends in allergy prevalence, those that have attracted most interest are the fall in exposures to infectious diseases.
However, since younger populations are less likely to be affected by extreme temperatures, temperature is unlikely to have contributed to IHD trends in those groups.
Chloroquine resistance (16 ), breakdown of vector-control operations (17 ), and HIV-1 may all have contributed to these trends (3, 4, 13 ).
Lastly, as sexual behaviour data were not available we were unable to adjust for any change in sexual risk behaviour – a decline for example could have contributed to decreasing trends observed.
Temporal increases in maternal body mass index (BMI), gestational weight gain, maternal height, diabetes, reduced maternal cigarette smoking and changes in sociodemographic factors have contributed to these trends [ 8- 11].
