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The phrase "have comprehensive understanding" is correct and usable in written English
It can be used when discussing someone's depth of knowledge or grasp of a subject. Example: "To excel in this field, one must have a comprehensive understanding of the underlying principles."
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While you're not likely to be expected to have comprehensive knowledge of literary terminology, understanding some of these key concepts will be important to your success.
Asked to comment on the allegations regarding Sims, Ms. Rosegay, the lawyer representing the auto recycling industry, said, "I've worked with the industry for 30 years, I have a comprehensive understanding of the industry's practices".
It suggests that compassion is not lacking and that service providers (across a wide range of disciplines) not only have a comprehensive understanding of the impact of injury on patients' lives, but also have knowledge of evidence identifying best models of care.
There is therefore considerable interest from industrial and academic organisations, who realise the capabilities this technology has in the design and implementation of products, to increase material choice and to have a comprehensive understanding of the fundamental material properties.
The ever-clever squirrels ("Not many people know this, but squirrels have a comprehensive understanding of aerodynamic engineering") decide to join their winged rivals in their travels.
"We're in the early stages of doing that, and we do not have a comprehensive understanding as of yet of where that oil is," Jane Lubchenco, the NOAA administrator, told Congress on Wednesday.
The goal of a case study is "saturation," that is to have a comprehensive understanding of a problem (Small 2009).
In order to have a comprehensive understanding of the BGSO method, 50 trials are done on every test system.
It is important to have a comprehensive understanding of heterogeneity and structural complexity of shaly reservoir under development.
Though young, they have a comprehensive understanding of all the layers of business, from product to engineering, to hiring, to managing people, he told me.
The proposed approach would help managers to have a comprehensive understanding of the plant with respect to the RE.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com