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In order to better understand the structural basis of ubiquitin UIM recognition, we have characterized changes in the structure and dynamics of ubiquitin upon binding of a UIM domain from the yeast Vps27 protein.
Some studies have characterized changes in hippocampal neural coding during incidental learning upon changes in environment [28] [34] and during task learning following a sudden change of task demands [35] [39].
We have characterized changes in DNA methylation in the superior temporal gyrus of patients with Alzheimer's disease, highlighting novel loci that facilitate better characterization of pathways and mechanisms underlying Alzheimer's disease pathogenesis, and improve our understanding of epigenetic signatures that may contribute to the development of disease.
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Changes of this nature are in good agreement with other studies to have compared fMRI steady-state and continuous task performance conditions against rest [13], [23] [26], but whereas in the current study, we describe these changes in the context of a multivariate analysis that has characterized changes in several networks simultaneously.
Beyond the decrease in humoral immunity, there is also a significant literature that has characterized changes in other components of the immune system in both precursor disease and frank MM.
Using NMR, we have solved the three-dimensional solution structure of an extended construct of the second PDZ domain of MAGI-1 (MAGI-1 PDZ1) alone and bound to a peptide derived from the C-terminus of HPV16 E6, and we have characterized the changes in backbone dynamics and hydrogen bonding that occur upon binding.
Furthermore, we have characterized phenotypic changes in response to enforced expression of IL-6 in tumor growth and resistance to chemotherapy [18].
A number of studies have characterized proteome changes after ethanol feeding in rats.
Here we have characterized transgenerational changes in rat maternal behaviour as a function of gestational and prenatal stress.
To identify regulatory mechanisms that initiate and coordinate the terminal differentiation of an epithelium, therefore, we have characterized the changes in gene expression that occur during a time course of Drosophila wing metamorphosis.
Members of Congress have put forward legislation in hopes of either gauging the toll of the new formula or stopping it; they have characterized the change as a way to cut education spending without facing the public.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com