Sentence examples for have been very substantial from inspiring English sources

"There have been very substantial gains at this point.

In many cases the extra amounts charged by churches have been very substantial.

There have been very substantial advances in the representation of workflows and in the engineering of workflow management systems (WMS).

"The cost savings achieved over the recent past have been very substantial and the cost of services provided by the health board compares very favourably with other health boards".

The support given locally by HSSCs does not appear to have been very substantial, at least as perceived by PHC organizations.

Regulatory and related costs associated with the introduction of new GM traits have been very substantial in the past, although the situation is now changing to some degree, at least outside of Europe.

"The progress has been very substantial, but the trend has tapered off in the last few years," Ms. Winthrop said.

"There has been very substantial investment in the facilities.

There has been very substantial research on recognition of genes and proteins, through several community evaluations, such as JNLPBA-2004 [26] and BioCreative [27], [28].

The genomes have been very dynamic with substantial changes through mutation, recombination, acquisition of genes in islands, and acquisition of cassettes in the major integron.

Those resources are going to be very, very substantial because we have been very successful in helping to stabilize the financial system, bring the cost of credit down, open up these markets at much, much lower cost than anybody anticipated.