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Yet, there have been substantial changes in the educational policy landscape over the past five years.
In recent decades, there have been substantial changes in mortality from urologic cancers in Europe.
Since 1991 there have been substantial changes in the ways that dictators assume power, in the tactics they use to maintain power, and in the ways in which they lose power.
Since the first reports of plasmid vaccines, there have been substantial changes made to the design of plasmid backbones, as well as to the antibiotic resistance markers chosen for clinical vectors compared with first generation vectors.
Since the 1990s, there have been substantial changes in the composition of immigrant groups to arrive in Spain.
Over the past 30 years, there have been substantial changes to New Zealand's immigration policy, though with a maintained focus on selecting migrants with skills valued in the New Zealand labour market and who are also likely to settle well in New Zealand.
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These results suggest that the risk of cigarette smoking resulting in adenocarcinoma of the lung has increased substantially over the same time interval during which there has been substantial changes in the characteristics of the cigarettes smoked, but the risk of developing squamous cell carcinoma has remained unchanged.
The CQC also said out that there has been a complete change of its executive team since the events detailed in the report, and that there had been substantial changes to its board.
Commons Speaker John Bercow ruled last week that the government could not return for a third attempt, unless there had been "substantial" changes to the proposals.
Rodents as major vectors have thrived at the expense of other species in regions where there has been substantial changes to the ecosystems, their numbers increasing even further under abnormal weather conditions.
Although there has been substantial change in the tech community over the past decade, early-stage venture capital operations and processes are for the most part the same as they were twenty years ago.
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CEO of Professional Science Editing for Scientists @ prosciediting.com