While large doses of the chemical, are known to cause nerve damage in people, acrylamide is deemed "a probable" human carcinogen by the Environmental Protection Agency because only rodents have been shown to develop tumors from exposure to it.
In addition, up to 41% of EVAR patients have been shown to develop post-procedural complications, with 20% subsequently requiring fluoroscopically based radiological re-intervention [1].
Similarly, children with IL-12 receptor β1 (IL-12Rβ1) deficiency have been shown to develop the severe form of TB, frequently [13].
While orthopedic trauma patients have been shown to develop greater rates of adverse events, no study has examined septic complications in isolation from other less serious conditions.
"Animal-Animal" chimeric embryos have been shown to develop into a target organ by using blastocyst complementation (Kobayashi et al. 2010; Matsunari et al. 2013).
Animal models of serum sickness, a circulating immune complex disease, have been shown to develop cellular infiltrates in the uvea [7].
In addition, niosomes have been shown to develop absorption of some drugs across cell membranes, and localize in targeted organs and tissues to elude the reticuloendothelial system [110].
Cytochromes c3 are polyheme c-type cytochromes characterized by low redox potentials, that have been shown to develop metal-reductase activity.
However, IFNs are species-specific and antibodies have been shown to develop in response to the high rHuIFN-α doses necessary for an effective therapy.
Critically ill patients have been shown to develop multifactorial weakness termed ICU-acquired weakness (ICUAW), and these patients are at risk of prolonged ICU lengths of stay, increased mechanical ventilation time, prolonged weakness and poor hospital outcomes [7 13].
On the other hand, conflict level expectations vs. the SCE have been shown to develop differentially across runs of trials with the same conflict level, arguing against the theory that the SCE is purely driven by expectation.
