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"To go to Staten Island — actually go there — would have been profoundly meaningless," he says.
Unlike Freddie, however, most of Hoffman's characters have been profoundly vulnerable, often disenfranchised misfits.
Like many conservatives, he claims to have been profoundly affected by Ayn Rand.
"To go to Staten Island actually go there would have been profoundly meaningless," he says.
"Had we used a more traditional approach," she continued, "he would have been profoundly deaf".
There can be no doubt that for many communities these past two weeks have been profoundly damaging.
The lives of these people, and of millions of others, have been profoundly altered by technology based on DNA.
Both audiences and critics have been profoundly unconvinced, and the show is "temporarily" off the air already.
But he also said that it would have been "profoundly wrong" not subsequently to honour the commitments he had given.
The effects have been profoundly inegalitarian -- and not just in the loss of manufacturing's blue-collar middle class.
The book consists of portraits of three activists — in China, Cuba, and Russia, respectively — whose political beliefs and actions have been profoundly influenced by the Internet.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com