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Several promising vaccine platform concepts have been engineered based on decorating OMVs with heterologous antigens.
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The darker sensor was engineered based on the light-sensitive protein Cph8, a chimeric sensor kinase.
A FA/acyl-CoA sensor was engineered based on the FadR protein and its associated regulator.
A minigene construct with A892>G mutation was engineered based on the previously described human tau minigene model [ 17].
Three dimensional ZnO dahlia-flowers have been engineered at room temperature relying on natural oxidation based aqueous chemical synthetic approach.
Based on the availability of fibres, technical textiles have been engineered to satisfy modern demands.
Based on this understanding, several versions of highly abbreviated synthetic micro-dystrophin genes (<4 kb) have been engineered (Fig. 4B) (Harper et al., 2002; Lai et al., 2009; Wang et al., 2000).
Alternatively, temperature induced cell detachment methods, based on the fact that ECM generally adheres to a hydrophobic surface rather than a highly hydrophilic surface, have been engineered.
Some have been engineered for better absorption.
As compared to the allosteric mode of activation that has been engineered for synthetic nucleic acid circuits based on oligonucleotide-sensing allosteric ribozymes and deoxyribozyme [17] [19], in this case there is no need for the presence of a third partner.
We have developed a novel immunotherapeutic TG1050 based on Ad5 that has been engineered to express three major antigens or antigenic domains encoded by the Hepatitis B virus (HBV) genome: the core, polymerase and HBsAg [ 3].
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