Sentence examples for have been changed considerably from inspiring English sources

Many of the global relationships and positive feedback loops relating to the inequality of myocardial oxygen supply and demand have not changed in many years, although molecular, electrophysiological, conceptual, and technological advances have been changed considerably.

Deputy Prime Minister Nick Clegg defended the reforms earlier, insisting the Bill had been changed "very considerably" since a pause in the progress of the legislation through Parliament last year.

Genes in this category are mostly metabolic enzymes, e.g., protein kinase, lipase and phosphatase; these might be expected to evolve slowly with respect to primary structure, but they offer interesting avenues for further investigation since their regulatory regions have clearly been changed considerably.

 The findings revealed that basic minimum needs at present have been considerably changed from the past.

Gomphotheres may have been able to considerably change the habitats they entered, in the same way African elephants do today, by destroying trees and turning woodland into grassland.

"The economics of investment banking is changing – has changed considerably – and that itself is driving the new generation of leadership in banks to recognise that it is in their own interest now to change the culture".

In order to account for the suggestions made by the third reviewer, the final section of the conclusion has been considerably changed.

The treatment of metastatic RCC (mRCC) has been considerably changed over the last 5 years due to the anti-tumor efficacy of two groups of targeted agents, namely agents that inhibit vascular endothelial growth factor (VEGF) signaling pathways and that inhibit mammalian target of rapamycin (mTOR) [ 2].

Security measures have been bolstered considerably.

Yet inventories have been drawn down considerably.

Over time, the way in which drug products have been licensed in the EU has changed considerably.