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The lesion that was in situ before chemotherapy may have become detectable in CT images owing to its modification to a homogeneous, hypoattenuating lesion with well-defined borders due to the effect of bevacizumab-containing chemotherapy.
If one assumes that upon tracking for longer than 5.5 hours, Tubb3-mGFP expression should have become detectable if Tis21-nucGFP positive AP daughTis21-nucGFP positiveternAPive possibilities as to the fate of these cells shouldaughtersidered.
Instead, the much higher rate at which new somatic alleles have become detectable in these patients indicates a unique combination of timing and magnitude of selection against their inherited allele.
With about an additional 3 volume doubling times beyond this, a majority of the remaining metastases would then have become detectable, as had been surmised from Fig. 3b.
False negative diagnosis may occur if an individual is screened before lesions have developed, but this can be avoided by screening after the age when all developed lesions have become detectable.
22 Thanks to the improvement in nutritional management in the second period, the role of postnatal nutrition may have become detectable in the more recent LIFT cohort before and after adjustment for breast feeding.
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Tg-on had become detectable in 1 of 14 patients, Tg and TSH levels did not significantly differ (p = 0.4 and 0.7) compared to the situation before radioiodine treatment.
By around the 50-cell stage, significant H3K36me3 has become detectable in the somatic cells of the embryo; this methylation is consistent with MES-4-independent, MET-1-dependent HMT activity that is coupled with zygotic transcription activity [ 17].
PBDEs are persistent organic chemicals, and some congeners can bioaccumulate; therefore they have become ubiquitous contaminants detectable in the environment, in animals, and in humans (Hites 2004; Sjodin et al. 2008b).
As assays have become more sensitive, however, debate exists regarding the significance of small but detectable increases in troponin.
ERα-, and in particular the 'triple-negative' subset of breast cancer lacking detectable ERα, PR, and Her2, has emerged as a challenge for systemic therapy now that successful targeted therapies have become available for the treatment of other phenotypic subgroups.
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