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Additionally, we have an "Activate", component, responsible for enabling or disabling the service quality control of all QoSControl components in the hierarchy.
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Thus, cells that have entered the tumor have an activated phenotype regardless of their starting phenotype.
Therefore, our data indicate that a large portion of the γδ T cells in the thymus of Id3−/− mice have an activated phenotype.
Almost all the networks obtained (with one exception) require protein 1 to have an activating PTM as well as a repressive autoregulatory loop.
These regulating proteins can have an activating or repressing effect on the expression of a gene.
KIR can have an activating or inhibitory effect on NK cell function.
Further, it would be vital to determine whether KIT immunopositive meningioma cases, indeed have an activated oncoprotein.
As many glioblastoma have an activating EGFR mutation [ 10, 11, 46], the first clinical studies with EGFR inhibitors had high expectations [ 25].
EpCAM+AFP+ HepCSCs have an activated Wnt/β-catenin signaling with a parallel increased expression of all four microRNA-181 family members.
Unlike T-cell acute lymphoblastic leukemia (T-ALL), in which more than half of patients have an activating mutation in Notch1 [ 8], a chromosomal translocation involving Notch loci or an activating mutation has yet to be reported in breast cancer.
The A375 cells do not have an activating mutation of AKT, PIK3CA, or N-ras, and express PTEN protein (MAD and KS-H, unpublished data).
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