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"We deal with tens of thousands of patients here who are positive, and a high percentage of them have adherence issues," said Mr. Weinstein.
Genes in these regions have previously been shown to have adherence functions [ 11, 35, 36, 51].
First, the study participants are less likely to have adherence issues, differential recall of symptoms, or placebo effects.
More than 35% of patients have adherence issues during their first 4 to 6 weeks of treatment 3 and by 2 years, 75% are considered only partially adherent.
Self-reporting has been shown to have adherence levels not different from unannounced pill count, visual analog scale and electronic drug monitoring [ 42].
Among the patients successfully interviewed, seven were excluded from the analysis because they did not have adherence data (they did not provide their pills during the home visit).
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Question: How has adherence been measured in recent prospective studies focusing on adherence to exercise programs among older people?
No children had adherence <80% by either method.
Sixteen percent had adherence <95% by VAS, and 31% had adherence <95% by clinic-based pill count.
The relatively good agreement between VAS and clinic pill counts (Kappa = 0.52; 95%CI 0.34,0.70) resulted from 70% of children having adherence >95% with both methods.
Thirty-three percent of the patients had adherence <60% (Fig. 2).
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