Indeed, interventional trials that have respected these basic rules have achieved improved clinical outcomes.
Newer versions of the SCRAM™ seem to have achieved improved reliability so that for research in field settings participants need only receive initial training in the use of the device without calibration before using it in their normal lives.
Previous studies that have introduced an enhanced clinical service to support the telemonitoring arm of a trial have achieved improved outcomes compared with the usual care available to people with COPD. 10 12 For example, telemonitoring in the context of an integrated care service 31 incorporating case management 35 or providing additional home visits 36 reduced hospital admissions.
24 In addition, some authors suggested that β2-agonists may improve pulmonary function in patients with HF. 25 Perhaps a plausible hemodynamic explanation is that COPD patients gradually achieved improved right ventricular function and may have achieved improved left ventricular function as well as NT pro-BNP levels to some degree, with ameliorating pulmonary function mediated by β2-agonists.
When followed up after a second winter, the households had achieved improved levels of thermal comfort, whilst reducing their winter energy costs by a further 9%.
GEM has achieved improved response rates and survival benefit since its approval for BTC treatment [2 4].
First shown in surgical neonates, but also in those less than 32 weeks at birth, prophylactic sodium supplementation from 7 35 days of life has achieved improved weight gain without increasing adverse events [57, 58].
When M=2, we can get the second-order LPFT, which has achieved improved performance in many applications such as radar imaging [11, 12], nonstationary interference excision in DSSS communications [13, 14], chirp signal detection [15], and source localization and tracking in nonstationary environment [16].
The method has achieved improved sensitivity and accuracy over the RNA z-test method (ie, ranking genes as targets based on normalized expression data, without any additional modelling or processing) and a competitive, alternative network-inference method, MNI [ 14].
Several techniques (e. g., charge interactions, layer-by-layer deposition, and self-assembly) have been employed to deposit the genes onto the substrates and have already achieved improved transduction performances compared to those of a solution-based delivery approach.
Recently, core-shell catalysts have been widely investigated in electrocatalysis and have achieved significantly improved activity and kinetics28,29,30,31,32,33,34,35.
