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Parents have a well established right to home educate and many thousands do so every year.
Many, like ylang-ylang, already have a well established hold on the perfume industry, but the scents as they are commonly used have gone stale.
Eph receptors and their ephrin ligands have a well established role in spine formation and synaptogenesis.
Liposomes were first proposed as vaccine carriers some time ago [9], and have a well established history in the pharmaceutical industry.
Although urban rural disparities occur, the rural areas have a well established network of government health services.
TNF inhibitors have been indicated for the treatment of RA for more than 10 years and, as a result, they have a well established safety profile.
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Google and Zoho are doing well here, and have a well-established base.
We have a well-established client base that continues to grow.
If you already have a well-established interest, how might this make a positive difference for others?
Our support staff to veterinarian ratio is high, and we have a well-established and loyal client base.
This really only works if you already have a well-established reputation and fan following, and ultimately would make things too complicated anyway.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com