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The departure in January of the executive chairman, Nicola Cortese, seemed to have a ruinous effect.
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But his determination to squeeze out the competition has had a ruinous effect in an unlikely place – his home town.
However, the expense of building the road from the beach (no financial assistance being provided by Trinity House, despite their regular use of the road following the construction of the lighthouses), the Villa and the general cost of running the island had a ruinous effect on the family's finances, which had been damaged by reduced profits from their sugar plantations in Jamaica.
I escaped without a fine, but for many, penalties incurred for vehicular offenses have a ruinous financial impact.
Irish politician Charles Stewart Parnell has a ruinous Victorian affair with a married woman.
As anyone who has read George Orwell knows, this had ruinous effects on some boys, but those who thrived, as John F. Kennedy did, believed that life was a knightly quest to perform service and achieve greatness, through virility, courage, self-discipline and toughness.
Technologies including genetic modification "may give excellent results in the laboratory, may be advantageous for some, but have ruinous effects for others", he argued.
Make no mistake, the excessive consumption of sugary soft drinks has ruinous effects on people's health, and government and policy must play a central role in tackling the obesity crisis.
"It has an effect.
He has survived a ruinous crash and come back stronger than ever.
In it, he wrote that by curtailing freedoms and tightening restrictions on civil society groups and the press, Mr. Putin had adopted "a ruinous and hopeless path".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com